Description

Research Overview

BPC-157 (Body Protection Compound 157, also known as bepecin or PL 14736) is a synthetic stable gastric pentadecapeptide — a 15-amino acid sequence derived from a protein found in human gastric juice. Its stability in gastric juice distinguishes it from many other research peptides and has made it a subject of significant investigation in gastrointestinal mucosal biology, cytoprotection research, and vascular signaling.

In controlled research environments, BPC-157 is studied for its apparent cytoprotective and organoprotective properties across multiple tissue types, including gastrointestinal mucosa, endothelium, musculoskeletal tissue, and nervous system tissue in preclinical models.

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Scientific Background

BPC-157 is characterized in the literature as a likely mediator of gastric cytoprotection and has been investigated across a broad range of preclinical models for its ability to maintain gastrointestinal integrity against noxious agents. Its molecular activity involves multiple interconnected pathways including VEGFR2 activation for angiogenesis, FAK-paxillin signaling for cell migration, JAK-2 pathway stimulation for cell survival, and Egr-1 gene upregulation for tissue repair gene expression.

BPC-157 demonstrates remarkable stability in human gastric juice for over 24 hours — an unusual property among research peptides that supports its investigation via oral administration routes in preclinical models. It has been evaluated in trials for ulcerative colitis and has entered phase 1 safety investigation in human subjects.

Molecular Information

• Peptide Type: Stable gastric pentadecapeptide (synthetic)
• Amino Acid Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
• Amino Acid Length: 15 amino acids
• Source Origin: Derived from protein sequence found in human gastric juice
• Research Classification: Cytoprotection and gastrointestinal biology research compound
• Purity: ≥99% (HPLC verified)
• Appearance: Lyophilized powder
• Storage: Stable at room temperature; refrigeration recommended for long-term storage

Quality & Analytical Standards

Each batch undergoes analytical verification to confirm identity and purity. Batch-specific Certificates of Analysis (COA) are maintained for all production runs and available upon request.

Research Use Only

This product is intended strictly for laboratory research purposes. Not approved for human or veterinary use. No therapeutic or diagnostic claims are made. BioStrata Research supplies materials exclusively for qualified research and analytical applications.